Engineering exosomes by three-dimensional porous scaffold culture of human umbilical cord mesenchymal stem cells promote osteochondral repair

Improving the poor microenvironment in the joint cavity has potential for treating cartilage injury, and mesenchymal stem cell (MSC)-derived exosomes dragon ball lg disney (MSC-Exos), which can modulate cellular behavior, are becoming a new cell-free therapy for cartilage repair.Here, we used acellular cartilage extracellular matrix (ACECM) to prep

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Investigating functional brain network integrity using a traditional and novel categorical scheme for neurodevelopmental disorders

Background: Current diagnostic systems for neurodevelopmental read more disorders do not have clear links to underlying neurobiology, limiting their utility in identifying targeted treatments for individuals.Here, we aimed to investigate differences in functional brain network integrity between traditional diagnostic categories (autism spectrum dis

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